PAREXEL
Topic 1 | Sections 3.1.1, 4.2, 4.3.2, 4.3.3

Change 3: Assessment of Lymph Nodes

RECIST 1.0:

  • No specific recommendations

RECIST 1.1:

  • Definitions provided for
    • Normal: short axis < 10 mm
    • Measurable (Target): short axis ≥ 15 mm
    • Non-measurable: short axis 10 to < 15 mm
  • Target nodes measured in the short axis (perpendicular to longest diameter)
    • More reproducible and predictive of malignancy
  • Short axes of target nodes to be added to the sum of longest diameters