PAREXEL
Topic 1 | 

Change 20: Best Overall Response

RECIST 1.1:

Overall Response First Timepoint Overall Response Subsequent Timepoint BEST overall response
CR CR CR
CR PR

SD, PD, OR PR

CR

SD

SD provided minimum criteria for SD duration are met. Otherwise PD

CR

PD

SD provided minimum criteria for SD duration are met. Otherwise PD

CR NE

SD provided minimum criteria for SD duration are met. Otherwise NE

PR CR PR
PR PR PR
PR SD SD
PR PD

SD provided minimum criteria for SD duration are met. Otherwise PD

PR NE

SD provided minimum criteria for SD duration are met. Otherwise NE

NE NE NE